【摘要】 目的了解15个短串联重复STR基因座在青岛地区汉族群体的遗传学数据。方法对来自青岛地区汉族的200个无关个体的血样,Chelex法提取DNA;,PCR复合扩增,采用A;BI的全自动遗传分析仪进行基因分型,用Matlab编程进行统计学处理。结果获得了D21S11,D7S820,D13S317,D19S433,D3S1358,D8S1179,CSF1P0,THO1,D16S539,D2S1338,VWA;,TPOX,D18S51,D5S818,FGA;十五个STR基因座的遗传多态性参数。结论 15个STR基因座的累计个人识别率和非父排除率较高,适用于法医学亲子鉴定和个体识别更多还原

【Abstract】 Objective: To know the population genetic data of 15 short tandem repeat(STR) loci in Chinese Han population in the Qingdao aren Methods: 200 cases of ACD-blood specimens were collected form the unrelated individuals in Qingdao,The DNA samples were extracted with Chelex methed and amplified by multiplex PCR technique,The PCR produces and afterward genetyped were analyzed by an automatic genetic analyzer of ABI,Statistical analysis was carried out Matrix Laboratory Results: This study of 15 loci of parameter on genetic polymorphisms were obtained.Conclusion: All of the 15 loci have higher combined discrimination power and the exclusion probability,it can meet the needs of the parentage testing and personal identification in forensic medicine.更多还原