【摘要】 目的利用双源CT分析升主动脉的弹性特点,探讨其在大动脉弹性功能评价中的应用价值。方法筛选56名健康受检者作为研究对象,按年龄分为3组(A组<40岁;B组:40~50岁;C组:>50岁)。每间隔5%RR间期进行数据重建并测量兴趣层面的平均直径及截面积,分析健康人群升主动脉的搏动规律及弹性特点。结果随心脏搏动,升主动脉达到最大及最小直径的RR时相分别为(24.02±4.99)%及(93.50±4.04)%,与心率无明显相关性(P>0.05);A、B、C组直径变化分别为(2.58±0.54)mm、(1.90±0.37)mm及(1.44±0.48)mm。动脉弹性随年龄增长而降低,各组间弹性差异有统计学意义(P<0.05)。结论升主动脉随心脏搏动产生规律性舒缩,其弹性随年龄增长而降低。双源CT在动脉弹性变化的无创监测中具有可行性及一定的临床价值。更多还原

【Abstract】 Objective To evaluate the elastic property of the ascending aorta(AA) using ECG-gated dual-source(DS) CT,and to analyze its application value in assessment of aortic elasticity.Methods Totally 56 healthy subjects were divided into 3 groups according to age(group A: <40 years old;group B: 40—50 years old;group C: >50 years old).Original data were reconstructed in 5% steps throughout the RR interval.The average diameter and area of the plane of interest were measured.The pulsatile rule and elasticity characteristic of AA were analyzed.Results The maximum and minimum average diameter phases of AA were at an RR interval of(24.02±4.99)% and(93.50±4.04)%.There was no significant correlation between the phases and the average heart rate(P>0.05).The diameter changes were(2.58±0.54)mm,(1.90±0.37)mm and(1.44±0.48)mm for Group A,B and C groups,respectively.There was age-dependent decrease in elasticity,and significant difference was found among 3 groups(P<0.05).Conclusion There is regular diastole and systole of the AA accompanied with the cardiac pulsation.Aortic elasticity decreases with age.As a non-invasive method,ECG-gated DSCT can be used in evaluation of arterial elasticity and has certain clinical application value.更多还原