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刮治法联合重组人干扰素α-2b凝胶治疗扁平疣临床疗效观察

The Clinical Effects of Verruca Planae with the Therapeutic Method of Scaling Combined With Recombinant Human Interferon a-2b Gel

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【作者】 李勇坚李艳军张桂英肖嵘文海泉

【Author】 LI Yong-jian1,LI Yan-jun1,ZHANG Gui-ying2,XIAO Rong2,WEN Hai-quan2(1 Derpartment of Dermatology and Venereology,The First Affiliated Hospital of University of South China,Hengyang 421001,China;2 Derpartment of Dermatology and Venereology,Xiangya Second Hospital,Central South University,Changsha 410011,China)

【机构】 南华大学第一附属医院皮肤科中南大学湘雅二医院皮肤科

【摘要】 目的观察刮治法联合重组人干扰素α-2b凝胶治疗扁平疣的临床疗效。方法将入选的56例扁平疣患者随机分为治疗组和对照组各28例,治疗组予刮治法联合重组人干扰素α-2b凝胶治疗,对照组仅予重组人干扰素α-2b凝胶外用,共治疗8周,两组患者均每周观察1次皮损变化情况,疗程结束后评价疗效。结果治疗8周后,治疗组痊愈19例(67.86%),显效4例(14.29%),好转3例(10.71%),无效2例(7.14%),有效率为82.14%;对照组痊愈6例(21.43%),显效3例(10.71%),好转4例(14.29%),无效15例(53.57%),有效率为32.14%;两组有效率差异有统计学意义(P<0.05)。结论刮治法联合重组人干扰素α-2b凝胶治疗扁平疣具有较好的疗效。

【Abstract】 Objective To observe the clinical effects of verruca planae with the therapeutic method of scaling combined with Recombinant Human Interferon α-2b Gel.Methods Fifty-six patients with verruca planae were divided into two groups randomly,treatment group and controlled group.Each group had 28 cases and both of them used externally Recombinant Human Interferon α-2b Gel.The treatment group receival the treatment of scaling in addition.The leision changes of the two groups were observed weekly,while curative effects were assessed after 8 weeks therapy.Results Twenty-eight patients of the treatment group completed the 8-week trial,including 19 cases(67.86%) cured,4(14.29%) remarkably effective,3(10.71%) effective,2(7.14%) ineffective.The total effective rate was 82.14 percent.While in the control group,6 cases(21.43%) cured,3(10.71%) remarkably effective,4(14.29%) effective,15(53.57%) ineffective,the total effective rate was 32.14 percent.The difference of effective rate between two groups was statistically significant(P<0.05).Conclusions The therapeutic method of scaling combined with Recombinant Human Interferon α-2b Gel is the more prominenly beneficial to patients with verruca planae.

【关键词】 扁平疣刮治法干扰素
【Key words】 Verruca planaeScaling methodIFNα-2b
  • 【文献出处】 中国医学文摘(皮肤科学) ,China Medical Abstract of Dermatology , 编辑部邮箱 ,2011年04期
  • 【分类号】R752.52
  • 【被引频次】1
  • 【下载频次】82
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