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狗舌草提取物对多发性骨髓瘤U266细胞株细胞毒作用研究
A Research on the Effect of Extracts of Tephroseris kirilouii Turez.Houlub on the Cytotoxicity of Multiple Myeloma U266
【摘要】 目的:研究狗舌草提取物对266细胞的细胞毒作用。方法:U266细胞株与狗舌草提取物共同培养,用CCK-8试剂检测细胞毒作用。结果:狗舌草提取物对266细胞有细胞毒作用,半数抑制(质量)浓度约为3.2mg.L-1。结论:狗舌草提取物对266细胞有体外细胞毒作用。
【Abstract】 Objective: To study cytotoxic effect of extracts from Tephroseris Kirilowii Turez.Houlub on U266.Methods:U266 cells were cultivated together with the extracts of Tephroseris Kirilowii Turez.Houlub.Cytotoxicity assay was tested by CCK-8.Results:Extracts of Tephroseris Kirilowii Turez.Houlub showed strong cytotoxicity against U266 cells.The IC50 was about 3.2mg·L-1.Conclusion:extracts of Tephroseris Kirilowii Turez showed strong cytotoxicity effect on U266 cells.
【关键词】 狗舌草提取物;
多发性骨髓瘤;
U266细胞;
细胞毒;
【Key words】 Tephroseris Kirilowii Turez.Houlub extract; Multiple myeloma; U266 cells; Cytotoxicity;
【Key words】 Tephroseris Kirilowii Turez.Houlub extract; Multiple myeloma; U266 cells; Cytotoxicity;
【基金】 烟台市科学技术发展计划项目(编号:2007139-11)
- 【文献出处】 中医药学报 ,Acta Chinese Medicine and Pharmacology , 编辑部邮箱 ,2011年01期
- 【分类号】R285.5
- 【被引频次】7
- 【下载频次】119