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循环伏安法测定输液中表柔比星的含量
Determination of Epirubicin Injection by Cyclic Voltammetry
【摘要】 目的:建立用循环伏安法测定输液中表柔比星含量的方法。方法:以裸玻碳为电极,用循环伏安法测量表柔比星还原峰高与浓度的关系。结果:表柔比星在1×10-7~1×10-5mol·L-1范围内呈现线性关系,r=0.997 0,高中低三种浓度加样回收率达98.2%以上。结论:此方法简单、方便,可用于输液中表柔比星含量的快速测定。
【Abstract】 Objective:To establish a cyclic voltammetry method for the determination of epirubicin injection.Method:Using glassy carbon electrode,the relationship between reductive peak and concentration of epirubicin was studied.Result:The calibration curve of epirubicin showed a good linearity(r=0.9970)within the range of 1×10-7-1×10-5mol·L-1,and the sample-adding recovery was above 98.2%.Conclusion:This method is specific,sensitive and accurate,and can be used to detect epirubicin injection.
【基金】 温州市科技局医疗卫生项目(编号:201001437)
- 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,2011年05期
- 【分类号】R927.2
- 【被引频次】7
- 【下载频次】90