【摘要】 目的:建立清胃黄连片的质量控制标准。方法:采用薄层色谱法对清胃黄连片中黄芩、黄连、黄柏、甘草、知母、桅子、赤芍进行定性鉴别,采用高效液相色谱法对清胃黄连片中的黄芩苷进行含量测定。结果:黄芩、黄连、黄柏、甘草、知母、桅子、赤芍可在不同的薄层条件下分别检出;利用高效液相色谱法测定制剂中黄芩的有效成分黄芩苷,黄芩苷在0.20～1.60μg范围内线性关系良好(r=0.999 8),平均回收率为98.46%,RSD为2.89%(n=6)。结论:该法专属性强,重复性好,可用于清胃黄连片的质量控制。更多还原

【Abstract】 Objective:To establish quality standard of qingwei huanglian tablets.Method:Radix Scutellariae,Rhizoma Coptidis, Cortex Phellodendri,Radix Glycyrrhizae,Rhizoma Anemarrhenae,Fructus Gardeniae,Radix Paeoniae Rubra in the tablets were identified by TLC;the content of baicalin was determined by HPLC.Result:Radix Scutellariae,Rhizoma Coptidis,Cortex Phellodendri,Radix Glycyrrhizae,Rhizoma Anemarrhenae,Fructus Gardeniae,Radix Paeoniae Rubra could be detected in different TLC conditions.The linear range of baicalin was 0.20-1.60μg(r = 0.999 8).The average recovery was 98.46%with RSD of 2.89%(n = 6).Conclusion: The method is specific and reproducible.It can be used for quality control of qingwei huanglian tablets.更多还原