【摘要】 目的观察体外冲击波碎石(ESWL)治疗输尿管中下段结石后,应用坦索罗辛辅助治疗的效果。方法对2009-12～2010-07 510例输尿管中下段结石行ESWL后的患者,采用双盲对比法分两组进行对比治疗观察,其中实验组(226例)在对照组(284例)治疗的基础上加用坦索罗辛。观察时间为20 d。结果实验组结石排净率为84.5%(191/226),对照组结石排净率为62.3%(177/284),实验组的排净率明显高于对照组(P<0.01)。结论坦索罗辛组与对照组比较,排净率明显提高,复碎率及碎后再次肾绞痛发生率明显降低,药物副作用少、症状轻。更多还原

【Abstract】 Objective To observe the effect of tamsulosin in the adjuvant therapy after the extracorporeal shock wave lithotripsy (ESWL) in the patients with middle and lower ureteral calculi. Methods From December 2009 to July 2010,after ESWL, 510 patients with middle-lower ureteral calculi were divided into two groups; the experimental group and the control group. The experiment was conducted by double-blind method. And the experiment group was added tamsulosin based on the control group. The observation lasted for 20 days. Results The stone-free rate of the experimental group was 84. 5% (191/226) , that of the control group was 62. 3% (177/284). The stonefree rate of the experimental group was significantly higher than that of the control group (P < 0. 01). Conclusion Compared with the control group, the stone-free rate of the tamsulosin group significantly increased, the re-broken incidence and the renal colic incidence after broken stone significantly reduced, with fewer side effects, and mild symptoms.更多还原