【摘要】 目的探讨纤维支气管镜(简称纤支镜)吸痰及灌洗在慢性阻塞性肺疾病急性加重(AECOPD)机械通气患者中的临床应用价值。方法 66例患者随机分为对照组和治疗组各33例。两组均给予全身抗感染、营养支持等治疗。治疗组予纤支镜肺泡吸痰和灌洗治疗,对照组常规吸痰治疗,两组进行疗效比较。结果治疗组的疗效优于对照组(P<0.05);治疗组血气分析变化、肺部感染控制窗时间、机械通气时间及平均住院时间优于对照组(P<0.05或P<0.01);治疗组成功撤机、院内死亡例数少于对照组(P<0.05)。结论 AECOPD机械通气患者行纤支镜肺泡灌洗可改善通气和预后,是安全、有效的。更多还原

【Abstract】 Objective To explore the velue of clinical application of fiberoptic bronchoscopy with bronchoalveolar lavage (BAL) in AECOPD patients with mechanical ventilation. Methods Sixty-six patients with mechanical ventilation were randomly divided into control group ( n = 33 ) and treatment group ( n = 33 ). All patients accepted anti-infection, nutritional support treatments. The patients in the treatment group were treated with BAL, others in the control group accepted routine treatment. The therapeutic effects in the two groups were evaluated and compared. Results The treatment effects in treatment group was better than that in control group (P <0. 05). The improvement of blood gas analysis in treatment group was better than in control groups ( P < 0. 05 ) , the time of pulmonary infection control window, the time of mechanical ventilation, length of stay in treatment group were shorter than those in the control groups (P <0. 05 or P <0. 01) , the number of success to remove ventilator, organs failure and hospital mortality in treatment group were less than those in the control group ( P < 0. 05 ) . Conclusion Fiberoptic bronchoscopy with BAL treatment could be safe and effective for AECOPD patients with mechanical ventilation.更多还原