【摘要】 目的探讨Th1/Th2细胞因子偏移对格雷夫斯病（Craves disease,GD）碘转化率之间的相关性。方法选诊断为GD要求¹³¹Ⅰ治疗的60例患者和30例健康对照者,分别测定IL-2代表Th1细胞因子,IL-6代表Th2细胞因子。结果 IL-6在GD组明显高于对照组（P<0.01）;IL-2水平明显低于对照组（P<0.01）。IL-2、IL-6及IL-2/IL-6与甲状腺碘转换率均无明显相关性（P>0.05）。结论 GD患者的Th1/Th2细胞亚群失衡以偏向Th2为主;Th1/Th2细胞的偏移与甲状腺的碘转化率无相关性。更多还原

【Abstract】 Objective To study the correlation between the drift rate of serum Thl/Th2 and thyroid I conversion rate in patients with Graves disease. Methods Sixty patients with Graves disease （ GD group） and thirty healthy people （control group） were selected and compared. In this study, IL-2 represented cytokines of Thl, IL-6 represented cytokines of Th2. Results IL-6 in GD group was obviously higher than that in the control group （P < 0. 01） ;IL- 2 in GD group was obviously lower than that in the control group （P <0. 01） ; There was no correlation between IL-2、IL-6、IL-2/IL-6 and ¹³¹I conversion rate. Conclusion The imbalance of Thl/Th2 cytokines in patients with GD was in favour of Th2. There was no correlation between the drift rate of Thl/Th2 cytokines and thyroid I conversion rate.更多还原