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硫软膏联合尤卓尔乳膏治疗小儿丘疹性荨麻疹50例的疗效观察
Effect of sulfur ointment combined with hydrocortisone butyrate cream for treatment of children papular urticaria
【摘要】 目的观察硫软膏联合尤卓尔乳膏治疗小儿丘疹性荨麻疹的临床疗效。方法将104例患者随机分为治疗组和对照组。治疗组50例用硫软膏联合尤卓尔乳膏混合后外涂患处,3次/d,连用6 d。对照组54例予恩肤霜外用患处,3次/d,连用6 d。结果治疗组用药后第2天的痊显率为74.0%,高于对照组的40.7%(X~2=11.70,P<0.005),治疗组治愈率为48.0%,高于对照组的25.9%(X~2=5.46,P<0.05),平均治愈时间治疗组为(3.08±1.09)d,短于对照组的(3.78±1.09)d(t=3.66,P<0.001)。结论硫软膏联合尤卓尔乳膏治疗小儿丘疹性荨麻疹较单纯使用皮质类固醇激素的思肤霜治疗起效快、疗程短、疗效显著。
【Abstract】 Objective To observe the effect of sulfur ointment combined with hydrocortisone butyrate cream for treatment of children papular urticaria. Methods One hundred and four patients were divided randomly into treatment group and control group. Fifty patients in treatment group were coated with the mixture of sulfur ointment and hydrocortisone butyrate cream on their skin lesions, three times a day for 6 days. Fifty-four patients in control group were coated with clobetasol cream on their skin lesions, three times a day for 6 days. Results Two days after treatment, the cure rate and significant efficiency rate in the treatment group and control group were 74. 0% and 40.7% respectively, treatment group was significandy higher than control group (χ~2 = 11. 70,P<0. 01). The cured proportion in treatment group (48. 0% ) was higher than that in control group (25. 9% ) with statistical significance (χ~2 = 5. 46,P<0. 05). The average healing time in treatment group (3. 08 ± 1. 09 days) was shorter than that in control group ( 3. 78 ± 1. 09 days) in which the difference was statistically significant (t = 3. 66, P < 0. 01). Conclusion The effect of sulfur ointment combined with hydrocortisone butyrate cream in the treatment of children papular urticaria is fast and significant, and the course of treatment is short.
【Key words】 Papular urticaria; Hydrocortisone butyrate cream; Sulfur ointment; Clobetasol cream;
- 【文献出处】 中国临床新医学 ,Chinese Journal of New Clinical Medicine , 编辑部邮箱 ,2011年03期
- 【分类号】R758.24
- 【下载频次】62