【摘要】 目的检测冠心病不同中医证型血浆一氧化氮(NO)的水平,为冠心病的中医辨证分型提供客观依据。方法 165例冠心病患者按中医辨证分为心血瘀阻、痰浊壅塞、阴寒凝滞、心肾阴虚、气阴两虚、阳气虚衰6型,另设正常对照组30例;分别检测各组NO水平。结果冠心病患者各中医证型组NO值较正常对照组明显降低,具有统计学意义。各型间比较,痰浊壅塞型及心血瘀阻型显著低于其他各型,阳气虚衰型显著低于阴寒凝滞型、心肾阴虚型及气阴两虚型。NO值:痰浊壅塞型<心血瘀阻型<阳气虚衰型<阴寒凝滞型<心肾阴虚型<气阴两虚型<正常对照组。结论 NO水平与冠心病严重程度有一定关系,可作为中医辨证分型的参考指标。更多还原

【Abstract】 Objective:To observe the changes of NO in different TCM syndromes of CHD patients and to provide the objective evidence of TCM syndromes differentiations.Methods:165 patients with CHD were divided into 6 syndormes including the stagnation of blood in heart syndrome,the retention of phlegm syndrome,the coagulation of cold syndrome,the deficiency of heart and kideny syndrome,the deficiency of qi and yin syndrome,the deficiency of yang and qi syndrome.Besides that,there were 30 patients in the control group.The levels of NO were observed in several groups.Results:The reductions of NO in the CHD patients were more significant than that in the control group.The NO levels of the retention of phlegm syndrome and the stagnation of blood in heart syndrome were lower obvious than those of the other syndromes.It in the deficiency of yang and qi syndrome was lower than those of tha coagulation of cold syndrome,the deficiency of heart and kidney syndrome.Conclusion:NO level gives a further demonstration that it is an indicator of the severity of CHD.It could be an objective proof for syndrome differentiation of TCM.更多还原