【摘要】 目的:探讨基因重组活化凝血因子VIIa(rFVIIa)在产科出血中的应用效果。方法:1例重症肝损害剖宫产术后腹部伤口缝合时大出血患者,在用止血药物、输注血制品等治疗无效的情况下,予以rFVIIa 3.6 mg静脉推注(60μg.kg-1)。结果:用药后伤口渗血明显减少,24 h后伤口无渗血渗液,10 d后伤口拆线,愈合良好。结论:rFVIIa用于剖宫产腹部伤口大出血有很好的治疗效果,无明显不良反应,为难治性的产科出血提供了一种新的治疗手段。更多还原

【Abstract】 Objective:To explore the efficacy of recombinant activated factor VII(rFVIIa) in obstetric hemorrhage.Methods:rFVIIa(60 μg·kg-1,iv) was applied to a serious liver dysfunction patient whose incision bleeding could not be stopped by hemostatic drugs and blood products after cesarean section.Results:Bleeding was significantly reduced and was stopped 24 h after rFVIIa was applied.The wound healed ten days later.Conclusion:rFVIIa shows good efficacy without significant side effects for incision bleeding after cesare an section,providing a new treatment for refractory obstetric hemorrhage.更多还原