【摘要】 目的:调查医务人员严重急性呼吸综合征(SARS)幸存者康复期的情绪、记忆和日常生活功能,探讨心身交互作用关系。方法:采用前瞻性研究。方便取样抽取北京三家医院因感染新型冠状病毒而患SARS的医务人员43名,并选取年龄、性别、受教育程度匹配的对照组41名。对照组来自这三家医院的医务人员,用抑郁自评量表(SDS)评估抑郁,视觉模拟疼痛评定量表(VAS)评定疼痛,加州洛杉矶听觉词语学习测验(WHO-UCLA AVLT)及Rey-Osterrieth复杂图形测验(ROCF)评定记忆,日常生活能力量表(ADLS)评估日常生活功能。抑郁按严重指数(被试总分/80)分为轻中重三个等级。结果:医务人员SARS幸存者存在持续和显著的抑郁(轻、中、重度抑郁分别占31%、35%和17%)和疼痛,与对照组相比,存在更多的词语插入错误(P=0.047)。疼痛与情绪(r=0.40,P=0.031)和日常生活功能得分(r=0.47,P=0.01)显著正相关。甲基强的松龙治疗时间与日常生活功能得分显著正相关(r=0.38,P=0.041)。结论:抑郁及疼痛症状是SARS幸存者需要持续关注和处理的问题,在SARS治疗中长期大量使用甲基强的松龙应当慎重。更多还原

【Abstract】 Objective:To investigate the emotional,memory and daily function as well as psychosomatic relations of health care worker in Severe Acute Respiratory Syndrome(SARS) survivors.Method: A total of 43 health care worker SARS survivors and 41 healthy control subjects in three hospitals in Beijing were assessed depression with the Self-Rating Depression Scale(SDS),pain with Visual Analogue Scale(VAS),daily function with Activities of Daily Living Scale(ADLS),and memory function with World Health Organization-University of California-Los Angeles Auditory Verbal Learning Test(WHO-UCLA AVLT) and Rey-Osterrieth Complex Figure Test(ROCF).The depression was classified according to the severity index(total score/80).Results:The cohort experienced lasting and striking depression(mild,moderate and severe depression were 31%,35% and 17%) and pain(VAS=5.2±2.2).Compared with the healthy control group,SARS survivors had more intrusion errors(P=0.047).Pain was positively correlated with emotion(r=0.40,P=0.031) and daily functioning(r=0.47,P=0.01).The duration of methylprednisolone treatment was also positively correlated with daily functioning(r=0.38,P=0.041).Conclusion: Depression and pain are the major problems of SARS survivors which should be concerned about and handled to the physicians in general or infectious disease hospitals.Long-term utilization and overdosage of glucocorticoid are cautioned against in SARS treatment.更多还原