【摘要】 植物螯合肽(phytochelatins,PCs)在植物解除重金属的毒性方面具有重要作用,其结构为(γ-Glu-Cys)n-Gly(n=2～11),它不是基因的编码产物,而是在植物螯合肽合成酶(phytochelatin synthase,PCS)的催化下以谷胱甘肽(glutathione,GSH)为底物合成的。PCS能够被金属离子激活,高度保守的N-端是催化结构域,而其C-端则是多变的。本文就PCS的结构,功能与催化机制以及PCS的最新研究进行了介绍。更多还原

【Abstract】 Phytochelatins (PCs),with a general structure (g-Glu-Cys)n-Gly (n=2–11),play an important role in heavy metal detoxification in plants.PCs are post-translationally synthesized directly from glutathione (GSH) by the enzyme phytochelatin synthase (PCS),of which the activity is dependent on the presence of heavy metals.The conserved N-terminal core domain of PCS functions as the catalytic domain,whereas the C-terminal region is highly variable.The review focused on the structure,functions and catalytic mechanisms of PCS,prospects were also included.更多还原