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颈静脉孔区颅内外沟通型神经鞘瘤的外科治疗

Surgical treatment of communicating skull base schwannomas in the jugular foramen region

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【作者】 李学记万经海吴跃煌刘绍严钱海鹏徐震纲唐平章

【Author】 Li Xueji1,Wan Jinghai1,Wu Yuehuang2,Liu Shaoyan2,Qian Haipeng1,Xu Zhen’gang2,Tang Pingzhang2 1.Department of Neurosurgery;2.Department of Head and Neck Surgery,Cancer Hospital,Chinese Academy of Medical Sciences, Beijing 100021,China

【机构】 中国医学科学院肿瘤医院神经外科中国医学科学院肿瘤医院头颈外科

【摘要】 目的总结颈静脉孔区颅内外沟通型神经鞘瘤的手术经验。方法回顾性分析10例颈静脉孔区颅内外沟通型神经鞘瘤的临床资料。肿瘤均由神经外科和头颈外科联合经颅-颈入路一期切除。结果 肿瘤全切除9例,次全切除1例。术后新出现面瘫1例;脑脊液鼻漏3例,再次手术修补1例;术前神经功能障碍加重3例。无手术死亡病例。随访18~60个月,神经功能障碍均明显好转,无肿瘤复发。结论神经外科和头颈外科联合经颅-颈入路手术切除是治疗颈静脉孔区颅内外沟通型神经鞘瘤,尤其是伴有明显的颈部扩展者的理想方法 。

【Abstract】 Objective To summarize surgical experience with communicating skull base schwannomas in the jugular foramen region.Methods Clinical data of 10 patients with schwannomas originating from jugular foramen region were analyzed retrospectively.One-stage tumor resection was performed by multidisciplinary cranial base team composed of neurosurgeons and head and neck surgeons via craniocervical approach.Results Total tumor removal was achieved in 9 cases and subtotal removal in 1.Facial palsy occurred in 1 case postoperatively,cerebrospinal fluid rhinorrhea in 3 and surgical repair in 1,preoperative dysfunction of cranial nerve aggravated in 3 and no patient died.During a follow-up of 18 to 60 months,the dysfunction of cranial nerve was improved in all the patients,and no tumor recurred.Conclusions The surgical resection by neurosurgeons and head and neck surgeons via craniocervical approach is a good method for communicating skull base schwannomas originating from jugular foramen region,especially for tumors with marked cervical extension.

【基金】 首都医学发展科研基金项目(编号:2009-2009);首都临床特色应用研究项目(编号:D101100050010041)
  • 【文献出处】 中国微侵袭神经外科杂志 ,Chinese Journal of Minimally Invasive Neurosurgery , 编辑部邮箱 ,2011年01期
  • 【分类号】R739.4
  • 【被引频次】8
  • 【下载频次】172
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