【摘要】 目的:了解真性红细胞增多症(PV)患者外周血中红细胞增多与红细胞存活时间长短的相关性。方法:采集10例真性红细胞增多症患者离体抗凝全血和10例正常人离体抗凝全血,放血当天测定钾以排除患者血浆钾和正常人的差异和外界的影响因素,然后定期测定真性红细胞增多患者和正常人离体血浆中钾的浓度的变化,以了解红细胞破坏的程度。结果:真性红细胞增多症患者组第五天到第十天的钾离子浓度变化,第十天到第十五天的钾离子浓度变化,第十五天到第二十天的钾离子浓度变化均比正常人的大(P<0.05)。结论:真红患者红细胞的存活时间比正常人的短,间接证明真性红细胞增多症患者骨髓造血增生。更多还原

【Abstract】 Objective: To understand the correlation of erythrocytosis and erythrocyte survival time in peripheral blood of PV patients. Methods: In-vitro anticoagulant whole blood was collected from 10 PV patients and 10 normal respectively,and determination of potassium concentration was conducted on the bloodletting day to exclude the difference of plasma potassium between PV patients and normal people as well as the environmental factors.Then the changes of plasma potassium level in PV patients and normal were determined periodically to comprehend the destructiveness of erythrocytes. Results: The potassium level change of PV patients was larger than that of normal in the fifth day to the twentieth day.Conclusion: Erythrocyte survival time of PV patients was shorter than that of normal,which indirectly indicated that bone marrow hyperplasia can occur in PV patients.更多还原