【摘要】 临床动物电击除颤实验无法精确测量放电电场在心脏上的实际分布情况,且存在诸多不便利和不安全因素。鉴于此,提出了一种基于心脏建模及有限元求解的心脏除颤电场分布仿真研究方法,心脏模型包含了完整的心房心室解剖结构和左右心腔,考虑了心肌细胞和血液的电阻率,然后采用有限元方法进行分析,并使用Abaqus集成环境进行求解,求解结果与文献报道的参考标准进行对比。仿真结果在除颤电压阈值和能量阈值方面与目前的植入式心脏复律除颤器(ICD)的临床应用效果具有相当的吻合度,能量阈值相对误差仅为10%,验证了所提出方法的可行性。更多还原

【Abstract】 Clinical animal defibrillation experiments can not measure the electrical field distribution of heart precisely,also with inconvenience and unsafety.Thereby,a method for studying heart defibrillation electric field distribution based on heart modeling and finite element solution was proposed in this paper.The heart model covers integrated anatomy of atria and ventricles,with taking resistivity of cardiac muscle cells and blood into account.And then,finite element method and Abaqus Integrated Environment was adopted.Lastly,the result was put into contrast with the benchmark.In defibrillation voltage and energy threshold,the simulation result coincided with the clinical effect of Implantable Cardioverter Defibrillator(ICD) very well,with the relative error of energy threshold limited to 10%,which verified the feasibility of the proposed method.更多还原