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外周血未染色大细胞在骨髓增生异常综合征早期诊断中的价值

The Value of large unstained cell in peripheral blood in the early diagnosis for myelodysplastic syndrome

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【作者】 张璞孙海英鹿群先刘琼

【Author】 ZHANG Pu,SUN Hai-ying,Lu Qun-xian,et al.Xuzhou Medical College Affiliated Hospital of Xuzhou 221002,China

【机构】 徐州医学院附属医院血液科

【摘要】 目的通过测定外周血未染色大细胞比率(LUC%),以期提高骨髓增生异常综合征(MDS)的早期诊断率。方法选取我院58例确诊为MDS的患者,并设30例对照病例,比较外周血中LUC%和骨髓形态学报告。结果 58例MDS患者中54例(93.1%)外周血LUC%高于正常,其中有45例(83.3%)经初次骨髓穿刺诊断为MDS,9例(16.7%)经2~3次骨髓穿刺诊断为MDS。对照组30例中有1例(3.3%)外周血LUC%高于正常者。结论外周血LUC%的增高有早期诊断MDS的价值。

【Abstract】 Objective The ratio of large non-stainned cells in peripheral blood(LUC%) is measured to improve the rate of early diagnosis of myelodysplastic syndrome(MDS).Methods The LUC% of peripheral blood and the reports of bone marrow morphology of 58 patients diagnosed with MDS in our hospital were investigated comparing with 30 control cases.Results The LUC% of peripheral blood of 54(93.1%) patients from 58 cases of MDS was higher than that of control.45 cases(83.3%) from the above 54 patients were diagnosed as MDS by means of initial bone marrow biopsy,and 9 patients(16.7%) were affirmed to be MDS after the bone marrow puncture for 2 to 3 times.There was only one case(3.3%) that the LUC% of peripheral blood was higher than that of the normal in 30 patients in control group.Conclusion The increase of the LUC% of peripheral blood is value of early diagnosis for MDS.

  • 【文献出处】 中国实用医药 ,China Practical Medicine , 编辑部邮箱 ,2011年11期
  • 【分类号】R551.3
  • 【被引频次】2
  • 【下载频次】40
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