【摘要】 目的 观察静脉滴注胺碘酮在急性冠状动脉综合征(ACS)伴快速房颤患者的临床疗效。方法 20例ACS患者伴新近发生快速房颤,静脉应用胺碘酮,先静脉注射负荷量后,继以静脉滴注维持观察房颤转复及心室率控制及不良反应。结果 20例患者心率用药后较用药前明显下降(P<0.01)。其中14例患者(70%)在24 h内转为窦性心律,3例用药后出现长R-R间期,3例出现窦性心动过缓,经停药或减药后恢复。结论静脉应用胺碘酮治疗ACS伴快速房颤是有效及安全的。更多还原

【Abstract】 Objective To observe the effect of amiodarone to fast atrial fibrillation in patients with acute coronary artery syndrome(ACS).Methods Twenty ACS patients with newly onset fast atrial fibillation were observed.After a load dose,intravenous amiodarone was administered continuously.Efficacy of amiodarone in the reversion of atrial fibrillation and the contro1 of ventricular rate as well as the side effects were observed.Results The ventricular rate after the administration of amiodarone in the 20 patients were respectively,significantly lowered than the rate before the drug was given(P<0.01).Atrial fibrillation was reverted to sinus rhythm with 24 hour in 14 of 20 case(70%).Long R-R intermitment observed in 3 patients,sinus bradycardia was occurred in 3 patients,cardiac rhythm in all the patients’returned to normal after reducing the dose or ceasing the medicine.Conclusion Intravenous amiodarone is effective and safe in the treatment of fast atrial fibrillation in patients with ACS.更多还原