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福建省首次检出Aichi病毒及其分子流行病学调查

First detection and molecular epidemiology of aichi virus in Fujian,China

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【作者】 吴冰珊沈晓娜王美爱严延生

【Author】 WU Bing-shan,SHEN Xiao-na,WANG Mei-ai,YAN Yan-sheng(Fujian Center for Disease Control and Prevention,Fuzhou 350001,China)

【机构】 福建省疾病预防控制中心

【摘要】 目的了解福建地区Aichi病毒的存在和流行情况。方法对2008-2009年福建省多家医院的5岁以下腹泻儿童粪便179份,采用RT-PCR方法进行分子流行病学调查。结果检出Aichi病毒阳性粪便1份。测序后与国外已发表的毒株比较,表明了所测定FJ081021毒株序列(GU459258)与Qld/2008/204/Australia最接近,同源性达98.1%,证实其为B型Aichi病毒。结论首次发现福建地区人群中存在Aichi病毒。

【Abstract】 A total of 179 stool samples collected from children with diarrhea were retrospectively tested for Kobuvirus genus member aichi virus by reverse transcription-polymerase chain reaction(RT-PCR).One sample from a 3-year-old boy was positive.The nucleotide sequence isolate was determined,analyzed and compared to known Aichi virus sequences,which turned out to be a member of genotype B.Kobuvirus /Human/FJ081021/2008/China(GU459258),wihich had 98.1% nucleotide identidy to Qld/2008/204/Australia.This is the first detection of Aichi virus with gastroenteritis in Fujian,China.

  • 【文献出处】 中国人兽共患病学报 ,Chinese Journal of Zoonoses , 编辑部邮箱 ,2011年02期
  • 【分类号】R181.3
  • 【被引频次】11
  • 【下载频次】94
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