【摘要】 目的总结术后肠梗阻的发生机制的研究进展,阐述术后肠梗阻的发生机制对临床诊断、治疗及预防的重要意义。方法分析总结近年来有关术后肠梗阻发生机制的文献报道。结果术后肠梗阻的发生与术后神经反射抑制、炎症反应、药物作用等多种因素有关,它是多种机制共同相互调节的结果。结论术后肠梗阻的胃肠道动力主要由神经反射、炎症反应及药物相互作用三种机制共同调节,三者在不同的时间段所起的作用不同,但又相互作用构成一个整体,其中炎症反应对术后肠梗阻的持续起着关键性作用。更多还原

【Abstract】 Objective To summarize the recent advancements in the researches on the pathogenesis of postoperative ileus and explain the clinical significances of postoperative ileus mechanisms for the diagnosis,treatment,and prevention. Methods Relevant literatures about the postoperative ileus mechanism published recently were collected and reviewed. Results The occurrence of postoperative ileus were related to postoperative nerve reflex inhibition,inflammatory response,effects of drugs,and other factors,it was a variety of mechanisms modulating each other. Conclusion The gastrointestinal motility of postoperative ileus is mainly regulated by neural reflexes,inflammatory reactions,and drug interactions,three of which act differently but as a whole in different time segments while the inflammatory response play a key role of postoperative ileus persistence.更多还原