【摘要】 目的研究galectin-3的结构、配体、组织分布与肿瘤的关系及其在几种甲状腺疾病中的表达情况。方法对相关文献进行综述分析。结果 galectin-3在正常细胞及肿瘤细胞中表达,调节细胞的生长、分化、黏附、凋亡和血管形成,参与肿瘤细胞的侵袭和转移。结论 galectin-3可作为鉴别甲状腺良恶性肿瘤的参考指标。更多还原

【Abstract】 Objective To investigate the structure,ligand,and tissue distribution of galectin-3,the relationship of galectin-3 with tumor and the expression of galectin-3 in several thyroid diseases.Methods Related articles were reviewed.Results Galectin-3 was expressed in normal and tumor cell that regulated cell growth,differentiation,adhesion,apoptosis,and angiogenesis,which participated invasion and metastasis of tumor.Conclusion Galectin-3 may be used to discriminate benign and malignant thyroid tumor.更多还原