节点文献
山西省娄烦地区北社鼠对杀鼠灵的敏感性研究
Susceptibility of Niviventer confucianus to warfarin in Loufan,Shanxi
【摘要】 目的测定北社鼠对杀鼠灵的敏感性,为检验该鼠的抗药性提供参数。方法实验室做单个笼养无选择摄食试验:雌雄分开,随机分组,按5个不同食毒期供给浓度为0.025%的杀鼠灵毒饵;用Bliss计算机软件,计算不同食毒期与对应死亡率之间的关系。结果北社鼠对杀鼠灵的敏感性,性别之间差异无统计学意义(Pb>0.05,PLFP50>0.05);故将雌雄数据合并计算,得毒力回归方程y=3.29+4.33x,LFP50、LFP95、LF99及其95%置信限分别为2.48(1.97~3.13)、5.96(3.92~9.06)和8.56(4.65~15.78)d。结论按世界卫生组织推荐的以致死99%敏感靶标鼠的食毒期(LF90)取整天数作为抗药性检验标准,山西省娄烦地区北社鼠对0.025%的杀鼠灵毒饵摄食期超过9 d存活即为抗性鼠。
【Abstract】 Objective To determine the susceptibility of Niviventer confucianus to warfarin.Methods Baits with 0.025% warfarin were randomly given in single-sex groups of five feeding periods.The time to mortality was analyzed using the Bliss software.Results There was no significant difference in the susceptibility between sexes(Pb>0.05,PLFP50>0.05).The LFP50, LFP95 and LFP99 of warfarin for N.confucianus were 2.48(1.97-3.13) days,5.96(3.92-9.06) days and 8.56(4.65-15.78) days, respectively.Conclusion According to the WHO-recommended LFP99-based criteria for rodent warfarin resistance, N.confucianus surviving more than 9 days under exposure to 0.025%warfarin were classified into the resistant strains.
【Key words】 Niviventer confucianus; Anticoagulant rodenticide; Warfarin; Susceptibility;
- 【文献出处】 中国媒介生物学及控制杂志 ,Chinese Journal of Vector Biology and Control , 编辑部邮箱 ,2011年06期
- 【分类号】R96
- 【被引频次】2
- 【下载频次】35