【摘要】 目的探讨我国长寿地区百岁老人慢性肾脏病(CKD)的患病情况及相关危险因素。方法选取7个中国长寿之乡的所有百岁老人,以及在该地区按百岁老人编码尾数随机选取的40~、60~、80~和90~岁人群为研究对象,进行CKD及相关危险因素的问卷调查、体格检查和血尿检测,采用非条件Logistic回归分析CKD的影响因素。结果在资料完整的363名百岁老人中,CKD患病率为50.41%(95%CI45.27%~55.56%),女性患病率高于男性;各年龄组间比较,女性CKD患病率都随年龄增加而升高,而男性的CKD患病率随年龄增加先升高后下降。多因素Logistics回归提示高尿酸血症、高TG、女性、贫血、增龄和高血压为CKD的危险因素。结论我国长寿地区百岁老人CKD患病率为50.41%,CKD的危险因素为高尿酸血症、高TG、女性、贫血、增年和高血压。更多还原

【Abstract】 Objective To investigate the prevalence of chronic kidney disease(CKD) of centenarians in longevity area in China and related risk factors.Methods All centenarians in 7 longevity areas were selected,as well as randomly selected aged 40~,60~,80~ and 90~ population in the same 7 areas.They were interviewed and received physical examination and measurements of urine and blood for renal damage as well as risk factor.Logistic regression was used to analyze CKD and its relevant factors.Results 363 centenarians with complete data were enrolled.The prevalence of CKD was 50.41%(95% CI 45.27% ~ 55.56%),the male had lower prevalence of CKD compared with the female in all age groups.The logistics regression model showed that hyperuricemia,high TG,smoking,sex,anemia,age and hypertension contributed to the development of CKD.Conclusions The prevalence rate of CKD of centenarians in longevity areas is 50.41%,hyperuricemia,high TG,smoking,sex,anemia,age and hypertension are risk factors of CKD.更多还原