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依达拉奉联合早期康复对脑梗死患者肢体运动功能的影响
Effects of Edaravone and Early Rehabilitation on Motor Function of Patients with Acute Stroke
【摘要】 目的:探讨依达拉奉联合早期康复训练对急性脑梗死患者肢体运动功能的治疗作用。方法:急性脑梗死偏瘫患者205例,分为A、B、C 3组,均按神经内科脑梗死治疗方案治疗。A组70例同时增加依达拉奉联合早期康复训练;B组65例配合单纯康复训练;C组70例不附加其他治疗。治疗前后采用美国国立卫生研究院卒中量表评分标准(NIHSS)、简式Fugl-Meyer运动功能积分(FMA)及修订的Barthel指数(BI)评定3组患者神经功能、肢体运动功能及ADL的变化,并进行临床疗效评定。结果:治疗4周后3组NIHSS、FMA及ADL评分均较治疗前明显升高(P<0.05),其中A组明显高于B、C组。临床疗效比较,A组痊愈率明显高于C组(P<0.05),总有效率明显高于B、C组(P<0.05)。结论:依达拉奉联合早期康复训练可明显促进住院急性脑梗死患者肢体运动功能的恢复,改善神经功能缺损水平及提高ADL。
【Abstract】 Objective: To investigate the effect of Edaravone and early rehabilitation on motor function of patients with acute stroke.Methods: 205 patients with acute cerebral infarction in our department from March 1,2009 to December 30,2010 were divided into three groups randomly: group A(Edaravone and early rehabilitation group,n=70),group B(early rehabilitation group,n=65) and control group(group C,n=70).Control group received routine therapy only.Group A received routine therapy,edamvone Edaravone and simple early rehabilitation physical therapy.Group B received routine therapy and simple early rehabilitation physical therapy.The Fugl-Meyer(FMA),the National Institutes of Health Stroke Scale(NIHSS) and Barthel Index(BI) were used to evaluate the efficacy and endpoints before and one month after treatment.Results: Four weeks after treatment,total effective rate in group A was significantly higher than in group B and group C(P<0.05).As compared with those before treatment,NIHSS,BI and FMA scores in three groups were significantly increased(P< 0.05).NIHSS,BI and FMA scores in group A were higher than those in group B and group C(P<0.05).Conclusion: Edaravone and early rehabilitation can significantly improve the motor function and daily life ability of patients with acute stroke.
【Key words】 acute stroke; edaravone; early rehabilitation; motor function;
- 【文献出处】 中国康复 ,Chinese Journal of Rehabilitation , 编辑部邮箱 ,2011年05期
- 【分类号】R743.3
- 【被引频次】5
- 【下载频次】39