【摘要】 目的了解奉贤区重点职业人群弓形虫感染情况,评估各类风险因子对职业人群弓形虫感染的影响。方法随机抽样方法调查兽医、厨师和屠宰工从业人员弓形虫感染的危险因素暴露水平,采用ELISA法检测血清弓形虫IgG抗体水平;应用多因素统计方法分析各类风险因子影响效应。结果共调查365人,弓形虫感染10人,兽医、厨师和屠宰工弓形虫感染率分别为0、3.95%和2.19%,不同职业人群感染率差异无统计学意义(P<0.05)。利用多因素非条件Logistic回归和主成因分析方法筛选出9个主要风险因子,建立人群感染的数学模型,性别(OR=11.50)、来源地(OR=18.01)和饮酒过量(OR=2.19)对弓形虫感染风险有显著影响(P<0.05)。结论奉贤区重点职业人群弓形虫感染率处于较低水平,犬猫养殖与接触、生食习惯等部分感染风险因子被有效控制;要进一步有效制约职业暴露风险,应重点加强职业人群的健康教育和制度管理,加强对肉制品产销链的有效监管。更多还原

【Abstract】 Objective To investigate toxoplasmosis and evaluate its influencing factors among persons in different occupations in Fengxian District.Methods A questionnaire survey of veterinarians,cooks,and butchers was conducted by random sampling.Levels of exposure to risk factors were determined.Blood sera were tested for Toxoplasma IgG using ELISA.Multivariate analysis was used to evaluate the influence of risk factors.Results In total,365 persons in different occupations were surveyed,and 10 were positive for Toxoplasma IgG.Veterinarians,cooks,and butchers tested positive at rates of 0%,3.95%,and 2.19%;the difference among different occupations was not significant(P<0.05).Multi-factor unconditional logistic regression and principal component analysis identified 9 major risk factors for use in a mathematical model of infection of persons in different occupations.Gender(OR=11.50),place of origin(OR=18.01),and overconsumption of alcohol(OR=2.19) markedly affected the risk of developing toxoplasmosis(P<0.05).Conclusion The level of toxoplasmosis is relatively low in Fengxian District,and some risk factors,like caring for a cat or dog,contact with a cat or dog,and eating raw food,have been effectively controlled.To further reduce the risk of occupational exposure,health education and systems management must be emphasized for different occupations,and effective monitoring of meat production and marketing must be enhanced.更多还原