【摘要】 目的调查和评价手外科Ⅰ类切口围手术期预防性抗菌药物应用情况,为加强围手术期抗菌药物的合理使用和规范管理提供依据。方法抽取2010年1-12月出院的手外科Ⅰ类切口手术患者病历,对围手术期预防性使用抗菌药物的合理性进行评价。结果 103例病例中抗菌药物预防使用率为100.00%;药物使用率排前3位的分别是一、二代头孢菌素占43.33%、头霉素类占30.83%和β-内酰胺酶抑制剂的复合剂占10.00%;103例患者中,63.11%的病例存在用药不合理现象,主要表现为用药档次过高占59.22%、用药时间过长占54.37%、用法、用量不正确占28.16%、预防给药时机不当占26.21%、更换药物无依据占12.62%等。结论手外科Ⅰ类切口围手术期预防性使用抗菌药物不合理现象较严重,应制定针对性的干预措施,促进围手术期抗菌药物的合理使用。更多还原

【Abstract】 OBJECTIVE To investigate and analyze the prophylaxis application of antibacterials in typeⅠincision during hand surgery perioperative period,in order to find evidence for strengthening the rational use and standard management of antibacterials. METHODS The medical records of discharged patients of typeⅠincision hand surgery between from Jan 2010 to Dec 2010 were selected to analyze the application rationality of antibacterials prophylaxis in perioperative period. RESULTS All 103 patients were used antibacterials.The top 3 types of antibacterials on the usage were the first and second-generation cephalosporins(43.33%),cephamycins(30.83%),β-lactamase inhibitor compound(10.00%).There was irrational prophylaxis use in 63.11%.The main forms of irrational use of antibacterials were as follows: too high level of medication(59.22%),long course of treatment(54.37%),incorrect dosage and usage(28.16%),incorrect time of using antibacterials(26.21%),changing drugs without basis(12.62%). CONCLUSION The irrational application of antibacterials prophylaxis in typeⅠ incision during hand surgery perioperative period is serious,targeted interventions must be developed to improve the rationality of application of antibacterials.更多还原