【摘要】 目的分析医院2004-2009年临床分离的病原菌分布及耐药性变迁,为临床诊断与治疗提供参考依据。方法对临床送检的标本进行细菌培养,并进行细菌鉴定及药物敏感试验,统计分析试验结果。结果 2004-2009年,临床分离主要革兰阴性菌中,铜绿假单胞菌最多,大肠埃希菌次之,肺炎克雷伯菌居第3位,所占比例分别为28.42%、28.41%、19.00%;主要的革兰阳性球菌中,以金黄色葡萄球菌为最多,占43.94%;在2004-2007年的4年中,铜绿假单胞菌、金黄色葡萄球菌对常用抗菌药物耐药率总体呈上升趋势,但是2008年以后出现下降趋势。结论临床应根据药敏结果合理使用抗菌药物,可减少耐药菌株的产生。更多还原

【Abstract】 OBJECTIVE To analyze the bacteria distribution and the variation of drug resistance of clinical isolates during 2004-2009 in our hospital for clinical diagnosis and treatment.METHODS The strains isolated from clinical samples were collected,the results of drug susceptibility test were analyzed.RESULTS Of the Gram-negative bacteria,the top 3 isolates were P.aeruginosa,E.coli and K.penumoniae,They accounted for 28.42%,28.41% and 19.00% respectively.S.aureus was the most of the Gram-positive cocci,accounting for 43.94%.Resistance rates to commonly used antibiotics of P.aeruginosa and S.aureus were increasing in the mass during 2004-2007,but it was decreasing.CONCLUSION We should strengthen rational use of antibiotics to reduce the drug resistant strains.更多还原