【摘要】 目的探讨血乳酸水平与重症肺炎预后的关系。方法依据重症肺炎患者入院28 d生存状况分为存活组及死亡组,回顾性分析两组入院后48 h动态血乳酸变化。结果重症肺炎患者入院48 h血乳酸水平,死亡组(2.91±1.54)mmol/L,存活组(1.73±1.05)mmol/L,死亡组高于存活组,差异有统计学意义(P<0.05);6 h血乳酸清除率死亡组(6.87±3.89)%,存活组(18.88±9.24)%,死亡组明显低于存活组,差异有统计学意义(P<0.01),提示动态血乳酸测定较单次血乳酸测定对重症肺炎患者预后更具有价值。结论动态监测血乳酸水平,尤其是6 h血乳酸清除率对判断重症肺炎预后具有较高的价值。更多还原

【Abstract】 OBJECTIVE To evaluate the relationship between serum lactate level and outcome of severe pneumonia.METHODS The patients were divided into survival group and death group according to the mortality of severe pneumonia in hospital at 28 days.The changes of serum lactate level were measured in 48h after admission.RESULTS In severe pneumonia patients,serum lactate level of death group(2.91±1.54)mmol/L was higher than survival group(1.73±1.05)mmol/L in 48h after admission(P<0.05),and 6h clearance rate of serum lactate in death group(6.87±3.89)% was significantly lower than the survival group(18.88±9.24)%(P<0.01).It appeared to be more valuable than a single serum lactate level in patients with severe pneumonia.CONCLUSION Monitoring of serum lactate levels,especially serum lactate clearance rate of 6h has high value with the outcome of severe pneumonia.更多还原