【摘要】 目的了解医院脑卒中患者肺部感染革兰阴性杆菌的耐药性,为临床合理使用抗菌药物提供试验依据。方法 246株细菌鉴定采用法国生物梅里埃公司VITEK-32全自动细菌分析系统;药敏试验采用K-B法进行。结果脑卒中患者肺部感染的主要革兰阴性杆菌为肺炎克雷伯菌、铜绿假单胞菌、鲍氏不动杆菌、大肠埃希菌及嗜麦芽寡养单胞菌,分别占24.8%、23.6%、19.9%、16.3%及8.5%;以上细菌均产生了严重的耐药性,尤其值得关注的是已出现了泛耐药菌株。结论医院应采取切实的监控措施,预防与控制脑卒中患者医院感染。更多还原

【Abstract】 OBJECTIVE To understand antimicrobial resistance of gram-negative bacilli(GNB) causing pulmonary infection in stroke patients and provide the experimental evidence for clinically reasonable use of antibiotics.METHODS The VITEK 32(bioMérieux) system was used to identify 246 isolates.The susceptibility testings were performed by K-B method.RESULTS The main pathogens causing pulmonary infection in stroke patients were Klebsiella pneunmoniae(24.8%),Pseudomonas aeruginosa(23.6%),Acinetobacter baumannii(19.9%),Escherichia coli(16.3%) and Stenotrophomonos maltophilia(8.5%).The serious antimicrobial resistance occurred in the above strains.The pan-drug resistant strains emerged.CONCLUSIONS The practical monitoring measures should be taken to prevent and control the nosocomial infections in stroke patients.更多还原