【摘要】 目的比较腹腔镜联合光动力(PDT)与其他方法姑息治疗晚期胰腺癌的疗效。方法 28例晚期胰腺癌患者随机分为两组,PDT组13例为腹腔镜联合光动力治疗,对照组15例,采用化疗、放疗、内置架植入和开腹姑息手术等治疗。结果 PDT组患者0.5、1、2年生存率为92.3%,76.9%,12.0%,对照组生存率为66.7%,42.3%和0%,PDT组生存率明显高于对照组,经Log-rank检验,差异有统计学意义(χ2=3.923,P<0.05)。结论腹腔镜联合光动力治疗晚期胰腺癌有效。更多还原

【Abstract】 Objective To compare the effect of the combination of laparoscopic surgery and photodynamic therapy and other palliative therapies as an initial treatment for patients with advanced-stage pancreatic carcinoma.Methods Twenty-eight patients with advanced-stage pancreatic carcinoma were divided into group A and B at random.Thirteen patients in group A were undergoed the combination of laparoscopic surgery and photodynamic therapy.Meanwhile,15 patients in group B were treated by other palliative therapies:chemotherapy,radiotherapy,stent implantation,and open abdominal surgery etc.Results The 0.5-,1-,2-year survival rates in group A and B were 92.3%,76.9%,12.0%,and 66.7%,42.3%,0%,respectively.The survival rates in group A was significantly higher than those of group B(χ2=3.923,P<0.05).Conclusion The combination of laparoscopic surgery and photodynamic therapy is effective to patients with advanced-stage pancreatic carcinoma.更多还原