【摘要】 目的:了解2型糖尿病(DM)患者、糖调节受损(IGR)人群和血糖正常人群患龋情况,探讨其易感因素。方法:对145名2型DM患者、140名IGR人员和149名血糖正常人员进行流行病学问卷调查、口腔检查和血糖、静态唾液流量、唾液pH值测定。结果:DM组、IGR组和对照组的患龋率分别为66.9%、72.1%、63.8%,三组之间比较,差异无统计学意义;龋均分别为3.79、2.44、2.81颗牙,DM组的龋均显著高于IGR组和对照组(P<0.05),IGR组的龋均与对照组比较,差异无统计学意义(P>0.05);龋失补牙数构成比DM组分别为25.6%,26.4%,48.0%,IGR组分别为28.1%、10.5%、61.4%,对照组分别为34.1%、28.2%、37.7%,DM组龋失补构成比与IGR组,与对照组比较,差异均有统计学意义(P<0.05);IGR组龋失补构成比与对照组比较,差异有统计学意义(P<0.05)。DM组和IGR组的唾液量(mL/10min)和唾液pH值均数显著低于健康对照组(P<0.05),而空腹血糖值均数显著高于健康对照组(P<0.05)。结论:DM人群比IGR人群和健康人群患龋严重,控制糖尿病将有助于降低龋齿数。更多还原

【Abstract】 Objective: To explore the caries status and their predisposing factors for individuals with type 2 diabetes mellitus(DM),with impaired glucose regulation(IGR) and with normal glucose tolerance(NGT) respectively.Method: One hundred and forty-five patients with DM,140 individuals with IGR and 149 individuals with NGT(served as control group) were randomly selected.Oral examination was carried out and fasting plasma glucose(FPG)levels,plasma glucose level of 2 hours post glucose-load(PG2h),resting salivary flow rates,salivary pH value were tested.Result: For DM,IGR and control group,the caries rate were 66.9%,72.1%,63.8% respectively with no significant difference among them.DMFT(caries mean)in DM group was significantly higher than that in IGR and control group(P < 0.05).The means of resting salivary flow rate and salivary pH value in DM and IGR group were lower than in the control group;while the mean of FPG value in DM and IGR group were higher than in the control group(P < 0.05).Conclusion: Patients with DM have more possibilities of dental caries than individuals with IGR or healthy control.Controlling diabetes mellitus may help to reduce the number of dental caries.更多还原