【摘要】 目的总结有机磷农药中毒气管插管患者非计划性拔管(Unplanned extubation,UE)的发生率,分析UE发生的相关原因。方法回顾性分析2009年1月至2010年12月我科收治的43例有机磷农药中毒气管插管患者年龄、性别、Ramsay评分、阿托品日平均用量、气道痰痂评分、使用气管导管型号等临床资料,评估UE发生率并筛查UE的临床危险因素。结果本组有机磷农药中毒气管插患者UE发生率为30.23%,单因素分析显示,UE组与非UE组Ramsay评分、阿托品日平均用量及气道痰痂评分差异有统计学意义,Logistics逐步回归分析显示Ramsay评分(OR=0.079)和气道痰痂评分(OR=7.029)与UE的发生独立相关。结论有机磷农药中毒气管插患者UE发生率较高,Ramsay评分低和气道痰痂评分高是发生UE的独立危险因素。有效镇静和强化气道管理可能有助于减少UE的发生,提高有机磷农药中毒患者的救治成功率。更多还原

【Abstract】 Objective To analyze the incidence and risk factors of unplanned extubation(UE) in organophosphorus pesticide poisoning patients with endotracheal intubation.Methods The prevalence and risk factors of UE in 43 organophosphorus pesticide poisoning patients with endotracheal intubation were retrospectively analyzed.Results The incidence of UE in organophosphorus pesticide poisoning patients with endotracheal intubation was 30.23 percent.Logistic regression analysis showed that Ramsay sedation score(OR=0.079) and sputum scab score(OR=7.029) were the risk factors of UE.Conclusions The incidence of UE in organophosphorus pesticide poisoning patients is relatively high.Ramsay sedation score and sputum scab score are the independent risk factors of UE.Effective sedation measures and airway management may reduce the incidence of UE and increase the successful rescue rate of organophosphorus pesticide poisoning patients.更多还原