【摘要】 目的探讨单心动周期实时三维超声心动图测量正常人左心室容积及收缩功能的可行性及准确性。方法健康志愿者60例,应用三维矩阵探头采集左心室三维图像,使用LVAnalysis软件测量左心室舒张末期容积(EDV)、收缩末期容积(ESV)及左心室射血分数(LVEF)。应用二维超声心动图双平面Simpson法测量EDV、ESV及LVEF值。同时分别记录两种方法图像采集和图像分析时间。结果 (1)双平面Simpson法、单心动周期实时三维超声心动图测得的EDV、ESV及LVEF值差异无统计学意义(P>0.05)。(2)单心动周期实时三维超声心动图与双平面Simpson法测得的LVEF值具有相关性(r=0.954,P<0.01)。(3)两种方法采集图像和分析图像时间差异均有统计学意义(P<0.05)。(4)单心动周期实时三维超声心动图观察者间EDV、ESV及LVEF的变异系数分别为5.61%、9.45%、8.17%,观察者内EDV、ESV及LVEF的变异系数分别为5.82%、10.34%、6.45%。结论单心动周期实时三维超声心动图作为一种无创的、崭新的三维成像技术,在采样方式和采样信息方面具有独特的优势,可以准确、快速的定量左心室容积及收缩功能,具有广泛的临床应用前景。更多还原

【Abstract】 Objective To validate left ventricular (LV) volume and left ventricular ejection fraction (LVEF) calculations with single cardiac cycle real-time three-dimensional echocardiography. Methods Three-dimensional images of LV were used in 60 healthy subjects by matrix array transducer, the LV end diastolic volume (EDV), LV end systolic volume (ESV) and LVEF were measured by LV analysis. At the same time, the EDV, ESV and LVEF from biplane Simpson’s method were measured as well. Meanwhile, the time of acquiring image and analyzing image were recorded. Results (1)There were no significant differences between single cardiac cycle real-time three-dimensional echocardiography and biplane Simpson’s method for ESV,EDV and LVEF (P>0.05). (2)There was excellent correlation between single cardiac cycle real-time three-dimensional echocardiography and biplane Simpson’s method for LVEF(r=0.954, P<0.01). (3)There was significant difference between the two methods for the time of acquiring image and analyzing image(P<0.05).(4)Interobserver and intraobserver variabilities of single cardiac cycle real-time three-dimensional echocardiography were 5.61% and 5.82% in EDV 9.45% and 10.34% in ESV, and 8.17% and 6.91% in LVEF, respectively. Conclusion As a non-invasive three-dimensional imaging technology, the single cardiac cycle real-time three-dimensional echocardiography has a unique advantage in sampling mode and sampling information, which can quantify left ventricular volume and contractive function rapidly and accurately with clinical significance.更多还原