【摘要】 目的研究体内的体脂含量(fat mass)和非脂质含量(lean mass)对正常女性骨密度的影响程度。方法 414例绝经前和1020例绝经后妇女参加本研究,采用美国Hologic Delphi A双能X线骨密度仪测定腰椎、左股骨骨密度和全身骨密度以及fat mass和lean mass。结果①各部位脂肪含量和肌肉含量呈显著负相关;②在青年女性和绝经前妇女中,Lean mass是决定腰椎、股骨近端各部位和全身骨密度的主要因素;③在绝经后妇女中,fat mass起主要作用。结论 Fat mass和lean mass对骨密度起不同的作用。更多还原

【Abstract】 Objective To investigate the effect of the contents of body fat mass and lean mass on bone mineral density(BMD) in healthy women.Methods Four hundred and fourteen premenopausal women and 1020 postmenopausal women were enrolled in this study.BMDs of the lumbar spine,the left proximal femur,and whole bones were measured using a dual-energy X-ray absorptiometry(DEXA).Fat mass and lean mass were also determined.Results ①Fat mass and lean mass were significantly negative-correlated in all sites.② Lean mass was a significant determinant of BMDs of the lumbar spine,the left proximal femur,and whole bones in premenopausal women.③Fat mass contributed most to BMD in postmenopausal women.Conclusion Fat mass and lean mass have different roles in BMD.更多还原