【摘要】 目的:系统评价中医正骨类手法治疗腰椎间盘突出症(LDP)的疗效。方法:通过计算机检索电子数据库、手工检索重要期刊及电话咨询目前正在进行临床研究等方式,全面收集中医正骨类手法治疗LDP的随机对照试验(RCT)并按Cochrane协作网推荐的方法进行系统评价。结果:共纳入2个RCT(143例患者),均为中文文献,2组试验均未观察到不良反应。Meta分析结果显示中医正骨类手法能提高LDP总有效率,差异有统计学意义[Peto-OR=10.73,95%CI(1.94,59.21)]。结论:现有的临床研究证据显示,与对照组比较,中医正骨类手法治疗腰椎间盘突出症有效,但因研究质量及研究样本的局限性,尚需进行高质量、大样本的随机对照试验予以进一步证实。更多还原

【Abstract】 Objective:To determine whether Chinese bone-setting manipulation can improve function in patients with lumbar disc protrusion(LDP).Methods: We searched the electronic bibliographic databases: CBM(1988~2010.8),CNKI(1988~2010.8),and VIP(1989~2010.8).We also did manual retrieval to identify other publ ished and unpubl ished data.Data were extracted and evaluated by two reviewers independently with a designed extraction form.The Cochrane Collaboration’s RevMan 5.0.was used for data analysis.Results:A couple of randomized trials involving 143 patients were included.No adverse events were reported.The results of meta-analyses indicated that Chinese bone-setting manipulation can increase the total effective rate in LDP patients compared to the control group,and the difference was statically significant [Peto-OR=10.73,95% CI(1.94,59.21)].Conclusion:The evidence available thus far indicates that Chinese bone-setting manipulation is effective in treating LDP.However,more high-quality trials are needed.更多还原