Objective To explore the effect of β-elemene on the reverse of multi-drug resistance and the expressions of the poly ADP-ribose polymerase protein(PARP) and P-glycoprotein(P-gp) in SGC7901/Adr cells.Methods MTT method was used to detect the sensitivity of cell and its reverse of multi-drug resistance.Intracellular accumulation of adriamycin in SGC7901/Adr cells was observed by fluorescent-spectrophotometry.Cell apoptosis was determined by flow cytometry after propidium iodide staining.Expressions of protein...
【基金】
国家自然科学基金资助项目(30901736);
辽宁省教育厅高校科研计划(L2010641)
【更新日期】
2011-12-28
【分类号】
R735.2
【正文快照】
网络出版地址http://www.cnki.net/kcms/detail/21.1227.R.20111128.1737.021.htmlReversal of Resistance to Adriamycin in Human Gastric Cancer byβ-elemeneZHANG Ye,SONG Na,LIU Yun-peng,QU Xiu-juan,HOU Ke-zuo,TENG Yue-e,ZHANG Jing-dong(Department of Medical Onco
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