【摘要】 目的:探讨我院药品不良反应(ADR)发生的特点及一般规律。方法:对我院2010年收集到的180例ADR报告按患者年龄、性别、给药途径、药品种类、ADR累涉及器官或系统及临床表现等进行分类统计与分析。结果:180例ADR报告中涉及的药品共有8大类,其中以抗微生物药引发的ADR比例最高(占35.00%),其次为中药及中药注射剂(占26.11%);静脉滴注比例较其他给药途径高(占82.22%);临床表现以皮肤及其附件损害比例最高(占37.78%),其次为全身性损害(占17.78%)。结论:临床应重视合理用药监测,积极上报ADR报告,避免或减少ADR的发生。更多还原

【Abstract】 OBJECTIVE:To investigate the general rules and characteristics of the adverse drug reactions(ADR)in our hospital.METHODS:180 ADR reports collected from our hospital in 2010 were analyzed statistically in respects of age,sex,route of administration,drug type,organ or system involved in ADR and clinical manifestations.RESULTS:180 ADR reports involved a total of 8 major categories of drugs,with the highest proportion of antimicrobials(accounting for 35.00%),followed by TCM and TCM injection(accounting for 26.11%);the proportion of intravenous route of administration was more than others(accounting for 82.22%);skin and its appendants damage accounted for the highest proportion of clinical manifestations(accounting for 37.78%),followed by systemic damage(accounting for 17.78%).CONCLUSION:Importance should be attached to rational drug use monitoring,reporting of ADR to avoid or minimize the occurrence of ADR cases.更多还原