【摘要】 目的:为临床合理、安全应用基本药物提供参考。方法:对2010年郑州市不良反应(ADR)监测中心收集到的各级医疗单位、经营企业上报的ADR报告进行统计、分析,探讨其特点和一般规律。结果:2010年ADR监测中心收集到完整报告共计10252份,其中国家基本药物所致ADR报告共计3021份(占29.47%);注射剂及静脉滴注最易引发ADR,各占62.31%、51.53%。结论:临床应加强ADR的监测工作,随着基本药物的推广使用,尤其应加强基本药物注射剂及静脉滴注给药ADR的监测工作,以减少ADR的重复发生。更多还原

【Abstract】 OBJECTIVE: To provide reference for rational and safe use of essential drugs. METHODS: ADR reports reported by medical institution at all levels and enterprises to Zhengzhou ADR Monitoring Center in 2010 were analyzed statistically. RESULTS: In 2010, ADR Monitoring Center collected a total of 10,252 copies of the full reports, including a total of 3 021 ADR reports of national essential drugs (accounting for 29.47%). Injections and intravenous infusion were most likely to lead to ADR, accounting for 62.31% and 51.53%, respectively. CONCLUSION: With the popularity and application of essential drugs, clinical monitoring of ADR should be strengthened, in particular ADR of essential drugs injection and intravenous infusion to reduce the incidence of ADR.更多还原