【摘要】 目的:调查我院重症监护室(ICU)鲍曼不动杆菌医院感染的危险因素和费用负担。方法:对我院ICU 2008-2009年发生鲍曼不动杆菌医院感染的54例患者的危险因素进行1:1病例对照研究。结果:发生鲍曼不动杆菌医院感染的独立危险因素为侵袭性操作、糖皮质激素的使用、未遵循降阶梯治疗;感染组与对照组患者平均住院天数、平均药品费用和平均住院费用差异有统计学意义(P<0.001)。结论:降低我院ICU鲍曼不动杆菌感染发生率及患者成本负担,可以从严格实施消毒隔离措施、合理使用糖皮质激素、遵循降阶梯治疗3方面进行控制。更多还原

【Abstract】 OBJECTIVE:To investigate the risk factors and cost in patients with nosocomial Acinetobacter baumannii infection in ICU of our hospital.METHODS:1:1 case control study was used to analyze risk factors of 54 patients with nosocomial Acinetobacter baumannii infection from ICU of our hospital during 2008-2009.RESULTS:Independent risk factors of nosocomial Acinetobacter baumannii infection included invasive operation,abuse of glucocorticoids drugs and no de-escalation therapy.There were significant differences in average hospitalization duration,average drug costs and hospitalization cost between 2 groups (P<0.001).CONCLUSION:To decrease the incidence of nosocomial Acinetobacter baumannii infection in ICU and corresponding cost,the following measures including disinfection and isolation,rational use of corticosteroids and de-escalation therapy should be practiced strictly.更多还原