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190株肠球菌的鉴定及药敏分析

Identification and sensitivity analysis of 190 strains of Enterococcus

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【作者】 冯恩航施中凯张兰萍

【Author】 FENG En-hang,SHI Zhong-kai,ZHANG Lan-ping(Heilongjiang Provincial Hospital,Harbin 150036,China)

【机构】 黑龙江省医院

【摘要】 目的了解黑龙江省医院肠球菌的菌种分布及对常用抗生素耐药性的现状。方法对2004年8月至2006年6月检出的190株肠球菌的菌种鉴定及药敏结果进行回顾性分析。结果粪肠球菌(46.3%)分离率下降;屎肠球菌(33.2%)、鹑鸡肠球菌(13.7%)分离率增加。耐药株检出率屎肠球菌为85.1%,粪肠球菌为75.0%,鹑鸡肠球菌为70.2%。青霉素和呋喃妥因对粪肠球菌引起的感染有一定的疗效,万古霉素,替考拉宁是治疗肠球菌引起感染的最佳选择。结论肠球菌已成为引起临床感染的重要致病菌,它的天然耐药和多重耐药的特性使得临床可选治疗药物范围狭窄。应防止耐万古霉素肠球菌株的产生。

【Abstract】 Objective To explore the current distribution and antibiotic resistance of enterococci in Heilongjiang Provincial Hospital.Method 190 enterococcus strains isolated from August 2004 to June 2006 were identified and their antimicrobial susceptibility consequence were retrospectively analyzed.Result The isolating rate of Enterococcus faecalis(46.3%) decreased,while the isolating rate of Enterococcus faecium(33.2%) and Enterococcus gallinarum(13.7%) increased.The detection rate of the persisters of Enterococcus faecium,Enterococcus faecalis,Enterococcus gallinarumis were 85.1%,75.0% and 70.2%,respectively.Penicilin and Nitrofurantoin had curativeeffect to the infection caused by Enterococcus faecalis.Vancocin and Teicoplanin were the best choice to treat the infection caused by Enterococcus.Conclusion Eterococcus has become the principal pathogenic bacteria that lead to clinical infection.Its natural characteristics of drug-resistance and multidrug resistantce narrow the range of curatives.So we should prevent the emergence of vancocin-resistant Enterococcus.

【关键词】 肠球菌构成比耐药性
【Key words】 EnterococcusProportionAntimicrobial resistance
  • 【文献出处】 中国微生态学杂志 ,Chinese Journal of Microecology , 编辑部邮箱 ,2011年04期
  • 【分类号】R446.5
  • 【被引频次】4
  • 【下载频次】69
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