【摘要】 目的探讨桐乡市第一人民医院颅脑损伤患者下呼吸道感染病原菌的分布及耐药性,帮助临床合理使用抗菌药物。方法采用VITEK-2细菌鉴定及药敏分析系统,对113例颅脑损伤患者下呼吸道感染痰标本分离出的病原菌进行鉴定和耐药性分析。结果 113例患者中共分离出病原菌179株,其革兰阴性杆菌122株,占68.1%,以肺炎克雷伯菌、铜绿假单胞菌和大肠埃希菌为主;革兰阳性球菌38株,占21.2%,以葡萄球菌属为主;真菌19株,占10.6%。结论颅脑损伤并发下呼吸道感染病原菌以G-菌为主,临床应重视病原菌的检查,开展病原菌耐药性的监测,合理使用抗菌药物。更多还原

【Abstract】 Objective To investigate the distribution of pathogens and their antibiotic resistance in head injuried patients with lower respiratory infections,and help doctors to use antibiotic reasonably.Method The pathogens isolated from 113 sputum specimens of lower respiratory infection of patients with head injuries were identified and tested by VITEK-2 microbe identification and drug-sensitivity system.Result A total of 179 strains pathogenic bacteria were obtained from the 113 patients.Among them 122 were Gram-negative bacteria,accounted for 68.1%,in which Klebsiella,Stenotrophomonas maltophilia and Enterobacter were the main Gram-negative bacilli;38 were Gram-positive bacteria,accounted for 21.2%,in which Staphylococcus were the main Gram positive cocci;19 were fungi,accounted for 10.6%.Conclusion The major cause of the bacterial infection of lower respairatory tract in head injuried patients is Gram-negative bacteria.Clinical doctors should pay attention to regular inspection of pathogenic infection and its drug resistance evaluation,and administer appropriate antibiotics.更多还原