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ω-3脂肪酸对胃癌新辅助化疗患者术后康复中的作用研究

Effect of Fatty Acids Omega-3 to postoperative rehabilitation in gastric cancer undergoing neoadjuvant chemotherapy

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【Author】 ZHANG Bin1,JI Sheqing1*,CHEN Xiaobing2,WANG Xiushen4,JIN Ge3,LUO Suxia2,HUA Yawei1,LIU Yingqiang11.General Surgery of Henan Tumor Hospital,Henan Province,Zhengzhou 450007,China;2.Medical Department of Henan Tumor Hospital,Henan Province,Zhengzhou 450007,China;3.Medical Department of the First Affiliated Hospital of Zhengzhou University,Henan Province,Zhengzhou 450052,China;4.Radiotherapy Department of Henan Tumor Hospital,Henan Province,Zhengzhou 450007,China

【机构】河南省肿瘤医院普通外科；河南省肿瘤医院肿瘤内科；河南省肿瘤医院放疗科；郑州大学第一附属医院心内科；

【摘要】目的:观察ω-3脂肪酸在胃癌新辅助化疗患者术后康复中的作用。方法:选择进展期胃癌40例,采用mFOLFOX-6方案术前化疗2周期,对照组(20例)术后常规治疗,治疗组(20例),术前1d及术后6d加用ω-3脂肪酸,观察两组患者手术后康复有无差异。结果:两组患者术后2、4、6dC反应蛋白(CRP)比较,差异具有统计学意义;两组患者手术后2、4、6dSIRS(全身炎症反应综合征)发生率,切口感染、吻合口瘘发生率,及术后静脉导管相关感染、血液感染及肺部感染率比较,差异无统计学意义(P>0.05)。结论:ω-3脂肪酸能降低患者炎症反应,促进患者康复。更多还原

【Abstract】 Objective:To evaluate the efficacy of Fatty Acids Omega-3 to postoperative rehabilitation in gastric cancer undergoing neoadjuvant chemotherapy.Methods:Patients with previously untreated advanced gastric cancer received mFOLFOX-6 neoadjuvant chemotherapy;twenty patients received Fatty Acids Omega-3 from one day preoperative to six days of postoperative the patients in the control group received basic treatment.Results:The difference of CRP 2,4,6 day of postoperative between two groups was statistically significant.Conclusion:Fatty Acids Omega-3 can degrade inflammatory reaction and encourage rehabilitation of gastric cancer undergoing neoadjuvant chemotherapy.更多还原

【关键词】进展期胃癌；新辅助化疗；氟尿嘧啶；奥沙利铂；根治术； ω-3脂肪酸；
【Key words】 Gastric cancer； Neoadjuvant chemotherapy； Fluorouracil； Oxaliplatin； Radical correction； Fatty Acids Omega-3；

【文献出处】中国当代医药 ,China Modern Medicine , 编辑部邮箱 ,2011年25期

【分类号】R735.2
【被引频次】6
【下载频次】77

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