【摘要】 目的:探讨复方醋酸棉酚片治疗绝经过渡期功血的临床效果。方法:将绝经过渡期功血患者98例随机分成两组,研究组50例,每天口服复方醋酸棉酚片;对照组48例,每天口服甲羟孕酮,连服3个月。随访至停药后3个月,对两组的治疗效果进行对比。结果:用药3个月研究组血清雌二醇、孕酮有不同程度下降(t分别为2.512、2.500,P均<0.05),促卵泡激素、黄体生成素明显上升(t分别为-3.045、-3.628,P均<0.01);停药3个月研究组发生闭经20例,月经量明显减少23例,月经正常5例;对照组有效治疗的31例患者中,无一例闭经,经量明显减少7例,月经正常9例,15例因月经再次紊乱增多改用其他治疗方法。研究组有9例患者用药1周内出现轻微恶心症状。结论:复方醋酸棉酚片治疗绝经过渡期功血的效果满意,副作用小,临床可推广使用。更多还原

【Abstract】 Objective:To observe the effect of compound gossypol acetic acid tablets in the treatment of menopausal transition dysfunctional uterine bleeding.Methods:98 patients with menopausal transition dysfunctional uterine bleeding were randomly divided into two groups,study group 50 patients took orally the gossypol acetic acid every day;control group 48 patients took orally depogeston every day,continued to take for 3 months.For 3 months visiting at any time to stopping the medicine,compared two sets of the treatment effect.Results:In using the medicine for 3 months research set,serum the estradiol and progesterone had different degree to descend(t=2.512 and 2.500 respectively,both P<0.05) and follicle stimulating hormone,luteinizing hormone obviously rose(t =-3.045 and-3.628 respectively,both P <0.01);Stopping the medicine research set for 3 months 20 patients developed amenorrhoea,23 patients had significant reduction in menstrual amount,menstruation of 5 patients returned to normal.Among 31 patients followed up in the control group,there was no one amenor hoea,7 patients had significant reduction in menstrual amount,menstruation of 9 patients returned to normal.15 patients were changed to use other treatmeant methods because of hypermenorrhea.In study group 9 patients used the medicine,and appeared slightly disgusted symptom within a week.Conclusion:Gossypol acetic acid treatment menopausal transition dysfunctional uterine bleeding is satisfaction.The side effect is small.It can be used widely in clinical.更多还原