齐拉西酮和氯丙嗪对精神分裂症患者认知功能影响对照试验

【摘要】 目的:比较齐拉西酮和氯丙嗪对精神分裂症患者认知功能的影响。方法:对46例精神分裂症患者随机分两组,经过齐拉西酮和氯丙嗪8周治疗,进行简明精神病评定量表(BPRS)、韦氏成人智力量表的记忆/不分心因子(FD/M)的检查评估。结果:患者经过8周治疗后BPRS总分均明显下降,但两药之间差异无显著性,服用齐拉西酮治疗的FD/M总分明显高于氯丙嗪。结论:齐拉西酮对认知功能的影响明显好于氯丙嗪。更多还原

【Abstract】 Objective:Comparison of ziprasidone and chlorpromazine on cognitive function of patients with schizophrenia.Methods:46 cases of schizophrenia were randomly divided into two groups after 8 weeks of ziprasidone and chlorpromazine treatment,the Brief Psychiatric Rating Scale (BPRS),Wechsler Adult Intelligence Scale memory/big heart factor (FD/M) of the inspection and evaluation.Result:After 8 weeks treatment in patients with BPRS total score decreased significantly,but the two drugs was no significant difference between the taking Ziprasidone treatment of FD/M total score was significantly higher than that of chlorpromazine.Conclusion:Ziprasidone on cognitive function was significantly better than chlorpromazine.更多还原