【摘要】 目的了解山东省报告的流行性乙型脑炎(乙脑)病例临床转归(后遗症和死亡)情况。方法对山东省2007～2008年报告的乙脑病例在发病6个月后,由县级疾病预防控制中心专业人员,采用入户或电话等方式进行随访调查。结果 2007～2008年共对报告的261例乙脑病例,在发病6个月后进行了随访调查,2年中的病例随访率分别为98.64%和100.00%,其后遗症发生率分别为17.01%和14.91%。其中最多的后遗症为记忆力或理解力障碍(76.19%),其次为语言障碍(66.67%)、流涎(33.33%)、瘫痪(28.57%),另外还有部分病例留有耳聋、痴呆、癫痫、吞咽困难、精神失常等后遗症。2007～2008年病死率分别为17.69%和19.30%,高于法定传染病报告系统的7.48%和7.89%,≥40岁乙脑病例的病死率高于其他年龄组。结论乙脑病例的后遗症发生率和病死率均较高,应加强对乙脑病例临床转归的监测。更多还原

【Abstract】 Objective To understand the clinical consequence(death or sequelae)for Japanese encephalitis(JE)Cases in Shandong province.Method JE cases reported during the year of 2007～2008 after 6 months of case onset were followed up by professional staff of county center for disease control and prevention(CDC)by visiting patient or telephone to them.Results Total 261 JE cases were followed up and the follow-up rate was 98.64% in 2007 and 100.00% in 2008 respectively.The incidence rates of sequelae for JE cases were 17.01% in 2007 and 14.91% in 2008.Among sequelae cases,the most sequelae was impediments of remembrance or intellect(76.19%),the second was the language barrier(66.67%).The incidence rates of JE cases with the salivating(33.33%)and paralysis(28.57%)were also at high level.Some cases had deaf,dementia,falling sickness,lunacy and so on.The fatality rates for follow-up JE cases were 17.69% in 2007 and 19.30% in 2008,which were much higher than the results from the National Notified Reported System for infectious diseases(7.48% and 7.89%).It also showed that the fatality rate for follow-up JE cases for ≥40 years old was much higher than that in other age groups.Conclusion The incidence rate of sequelae and fatality rate for JE cases was high.The surveillance for the clinical consequence of JE cases should be enhanced in China.更多还原