【摘要】 目的评价福建省2009年麻疹减毒活疫苗(Measles Attenuated Live Vaccine,MV)强化免疫活动(Supplementary Immunization Activities,SIA)效果。方法综合分析SIA接种率、人群抗体水平和麻疹监测系统资料。结果 MVSIA共接种8月龄～14岁目标儿童5544453人,报告接种率和调查接种率均>95%,免疫后人群麻疹抗体阳性率和几何平均滴度显著升高,麻疹发病率较SIA前下降了96.03%。从SIA后1个月算起,1年的时间全人群麻疹发病率为0.14/10万(2009年4月10日～2010年3月31日)。但≥15岁病例构成达50.98%。结论福建省2009年MVSIA效果显著,发病率已降至<1/10万。为保持SIA取得的成果,应在做好常规免疫的基础上,适时开展后续免疫。更多还原

【Abstract】 Objective To evaluate the effect of measles attenuated live vaccine(MV)supplementary immunization activities(SIAs)in Fujian province in 2009.Methods Comprehensively anslysing the data of the immunization coverage rate of MV SIAs,antibody level and the data of Measles Surveillance System.Results Total 5 544 453 targeted children of 8 months-14 years old were vaccinated,both reported and survey coverage were >95%,measles IgG antibody positive rate and the GMT level of the population immunized increased significantly.Measles incidence rate decreased to 96.03% after supplementary immuization activities.The measles annual incidence rate was 0.14/100 000 after immunization between Apr 2009 and Mar 2010.The cases aged ≥15 years have a significant increase,the proportion of cases reached by 50.98%.Conclusion The incidence of measles fell to <1/100 000 after MV SIAs In order to remain the achievements of SIA in Fujian province in 2009,the routine immunization coverage rate and continue follow-up campaign should be conducted in time.更多还原