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5-氨基酮戊酸-光动力疗法治疗复发性尖锐湿疣

Clinic Effect of Photodynamic Therapy for Recurrent Condyloma Acuminatum

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【作者】 刘金丽胡白蒋法兴张思平赵政龙吴爱丽廖理超

【Author】 LIU Jin-li,HU Bai,JIANG Fa-xing,ZHANG Si-ping,ZHAO Zheng-long,WU Ai-li,LIAO Li-chaoDepartment of Dermatology,Anhui Provincial Hospital,Hefei 230001,China

【机构】 安徽省立医院皮肤性病科

【摘要】 目的评价5-氨基酮戊酸-光动力疗法(ALA-PDT)治疗复发性尖锐湿疣的临床疗效。方法复发性尖锐湿疣患者62例,以5-ALA水溶液湿敷患处,3 h后以635 nm半导体激光照射,能量密度261 J/cm2,照射时间20 min,每周治疗1次。治疗后6个月判断治愈率及不良反应。结果 62例患者治愈率为87.1%。主要的不良反应为局部可忍受的刺痛,1例患者肛门口处出现浅表瘢痕。结论 ALA-PDT治疗复发性尖锐湿疣安全可靠,疗效满意。

【Abstract】 Objective To assess the efficacy of photodynamic therapy on recurrent condyloma acuminatum by aminolevulinic acid(ALA-PDT).Methods Sixty-two patients with recurrent condyloma acuminatum were given ALA-PDT once a week.The effect and the adverse reaction were examined after 6 months follow-up.Results The cure rate of recurrent condyloma acuminatum was 87.09%.The main adverse reaction was local tolerable sharp pain.Superficial scar only occured in one patient.Conclusions ALA-PDT for recurrent condyloma acuminatum is safe and has a good effect.

  • 【文献出处】 中国激光医学杂志 ,Chinese Journal of Laser Medicine & Surgery , 编辑部邮箱 ,2011年02期
  • 【分类号】R752.53
  • 【被引频次】18
  • 【下载频次】218
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