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相干对比成像在可疑心源性胸痛危险分层中的应用

Application of Coherent Contrast Imaging in Risk Stratification for Patients with Suspected Cardiac Chest Pain

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【作者】 刘婷婷陈小林汤立军余泽洪文达辉查道刚刘伊丽

【Author】 Liu Tingting,Chen Xiaolin,Tang Lijun,et al 1.Department of Cardiology,Institute of Cardiovascular Research,People’s Hospital,Jiangmen 529000 China 2.Department of Cardiology,Nanfang Hospital,Nanfang Medical University,Guangzhou 510515 China

【机构】 江门市心血管病研究所、江门市人民医院超声科江门市心血管病研究所、江门市人民医院心内科南方医科大学附属南方医院心内科

【摘要】 目的探讨相干对比成像(CCI)技术在无ST段抬高的可疑心源性胸痛患者危险分层中的应用价值。方法 203例无ST段抬高的可疑心源性胸痛患者在常规临床评估后用CCI技术行心肌声学造影(MCE),评价左心室局部心肌运动功能(RF)和心肌灌注(MP)。观察48 h(早期)和1年(晚期)随访期内急性心肌梗死、不稳定型心绞痛、心力衰竭和死亡等事件的发生情况。结果在203例患者中,33例(16.3%)发生早期事件,59例(29.1%)发生晚期事件。RF异常显著增加常规临床评估及心电图预测心脏事件的价值(P<0.000 1),MP异常将进一步提高预测价值(P<0.000 1)。结论 CCI在可疑心源性胸痛患者早期危险分层和处理中发挥重要作用。

【Abstract】 Objective To explore the incremental value of coherent contrast imaging(CO) over routine evaluation in risk stratification for patients with chest pain(CP) and no ST-segment elevation.Methods In addition to routine clinical evaluation,203 patients with suspected cardiac CP and no ST-segment elevation were evaluated for left ventricular regional function(RF) and myocardial perfusion(MP) using myocardial contrast echocardiography (MCE).Acute myocardial infarction,unstable angina pectoris,congestive heart failure(CHF) and cardiac-related death were considered as events within 48 h(early) and 1 year(late).Results Of the 203 patients studied,33 (16.3%) had early events,and 59(29.1%) had late events.Abnormal RF increased the prognostic information of clinical and EKG variables significantly(P<0.0001).And abnormal MP could further increase prognostic information significantly(P<0.0001).Conclusions CCI could be a valuable tool in the early triage and management of patients with suspected cardiac CP and no ST-segment elevation.

【基金】 江门市科技计划项目(No.08-5-9)
  • 【文献出处】 中国超声医学杂志 ,Chinese Journal of Ultrasound in Medicine , 编辑部邮箱 ,2011年09期
  • 【分类号】R540.45
  • 【被引频次】2
  • 【下载频次】19
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