【摘要】 目的探讨经阴道彩色多普勒超声病灶内微血管情况与早期宫颈癌预后的关系。方法对早期宫颈癌患者37例临床资料进行回顾性分析,全部患者均行宫颈癌根治术,术前均经阴道彩色多普勒超声检查,评估病灶内血管情况(无少量,丰富)及记录搏动指数(PI)。结果经阴道彩色多普勒超声提示早期宫颈癌病灶血管丰富与淋巴结转移、间质浸润深度≥10 mm、脉管受累、肿瘤直径≥18.0 mm及宫旁受累有相关性。经阴道彩色多普勒超声提示早期宫颈癌病灶血管丰富者术后需要治疗的机率大。经阴道彩色多普勒超声提示早期宫颈癌病灶血管无-少量及PI<0.82,或病灶血管丰富及PI>0.82或PI≤0.82者术后需要治疗的机率大。结论早期宫颈癌病灶的血管生成情况与患者预后有一定的关系。宫颈癌经阴道彩色多普勒超声病灶血管丰富及PI≤0.82与患者是否需要术后治疗有相关性。更多还原

【Abstract】 Objective To evaluate transvaginal color Doppler ultrasound(TVCD) angiogenic parameters in cervical cancer prognosis.Methods 37 treated women with early cervical cancer were retrospectively analyzed,and examined by TVCD prior to surgery.Subjective assessment of the amount of vessels within the tumor(scanty-moderate or abundant) and pulsatility index(PI) was recorded.Results Tumors with "abundant" vascularization were significantly associated with pelvic lymphnode metastases,depth stromal invasion(≥10 mm),lymph-vascular space involvement, tumor diameter(≥18.0 mm),and parametrial involvement.Postoperative treatment was significantly more frequent in patients with "abundant" vascularization.The presence of scanty-moderate vascularization with PKO.82 or abundant vascularization with either PI>0.82 or PI<0.82 was associated to high-risk groups.Conclusions The results are consistent between tumor angiogenesis and prognostic factors."Abundant" vascularization and PKO.82 may be related to postoperative treatment due to risk factors.更多还原